| Time | Session/Location | |||
|---|---|---|---|---|
| 07:00 - 09:00 | ES-ISHR council meeting - Room 202 |
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| 08:00 - 09:00 | Registration and Refreshments - Foyers of Teaching and Learning Building |
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| 09:00 - 10:00 |
Plenary session 2 - Lecture Theatre 1 Ketty Schwartz Award Lecture Gianluigi Condorelli, Humanitas University, Italy Session Chair: Frank Lezoualch, University of Toulouse, France |
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| 10:00 - 10:30 | Refreshment Break - Foyers of Teaching and Learning Building | |||
| Lecture Theatre 1 - Teaching and Learning Building |
Lecture Theatre 2 - Teaching and Learning Building |
G15 - Muirhead Tower |
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| 10:30 - 12:00 | Session 7 - Determinants of the Interorgan Crosstalk Invited Speakers: (20 minutes each) Carolina Greco, Humanitas University, Italy Circadian mechanisms Roger Foo, National University of Singapore, Singapore Cardiovascular, Kidney, Liver, and Metabolic Interactions in Heart Failure: Breaking Down Silos Genevieve Derumeaux, University of Paris Est-Creteil, France Aging at the Crossroads of Organ Interactions: Implications for the Heart Selected Abstracts: (15 minutes each) O13 - Abbie Hayes, University of Birmingham, UK Renal dysfunction induces early atrial electrophysiological remodelling independent of hypertension and ventricular structural disease: partial reversal by SGLT2 inhibition O14 - Tania Zaglia, University of Padua, Italy Neonatal Sympathetic Denervation Prevents Disease Manifestation in Desmoglein-2–linked Arrhythmogenic Cardiomyopathy Session Chairs: Melanie Paillard, University Claude Bernard Lyon 1, France Gabriele Schiattarella, Charite University Hospital, Berlin, Germany |
Session 8 - From Epigenetics to Precision Targets Invited Speakers: (20 minutes each) Ralf Gilsbach, University of Heidelberg, Germany Functional interpretation and modulation of cardiac regulatory elements Susana Pereira, Universidade de Coimbra, Portugal Maternal Programming of Offspring Cardiovascular Function Llew Roderick, KULeuven, Belgium Epigenetics in heart failure Selected Abstracts: (15 minutes each) O15 - Azra Husetić, University of Amsterdam, The Netherlands Exploring the Role of Calcineurin A in Cardiomyocyte Cell Cycle Re-entry for Post-injury Regeneration O16 - Parul Gupta, University Hospital Heidelberg, Germany Zeb1-Dependent Transcriptional Programs Underlie Female-Biased Cardiac Dysfunction Session Chairs: Monika Gladka, University Medical Center Amsterdam, The Netherlands Mauro Giacca, King's College London, UK |
Session 9 - Proteostasis in Heart Failure Invited Speakers: (20 minutes each) Zhao Wang, City of Hope National Medical Center, USA Role of protein turnover in heart failure Izhak Kehat, Technion-Israel institute of technology, Israel Subcellular protein translation in HF Mirko Völkers, University Hospital Heidelberg, Germany, Protein translation control Selected Abstracts: (15 minutes each) O17 - Maya Noureddine, University of Birmingham, UK Mechanistic insights into an α-actinin-2 variant: Linking functional impairment to biophysical alterations in hypertrophic cardiomyopathy O18 - Niels Pietsch, University Medical Center Hamburg, Germany Microtubule de-/tyrosination status regulates hiPSC-cardiomyocyte proliferation, autophagy, and hypertrophy Session Chairs: Manuel Mayr, Imperial College, London, UK Lucie Carrier, University Medical Center Hamburg-Eppendorf, Germany |
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| 12:00 - 13:30 | Lunch and Poster Session 2 - (Room 118/119) | |||
| Lecture Theatre 1 - Teaching and Learning Building |
Lecture Theatre 2 - Teaching and Learning Building |
G15 - Muirhead Tower |
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| 13:30 - 15:00 |
Session 10 - Scintica Sponsored Session - Imaging Across Scales in Cardiovascular Research Introduction to Scintica (5 minutes) Invited Speakers: (20 minutes each) Mona Malek Mohammadi, University Hospital Bonn, Germany New frontiers in cardiac regeneration Juma el-Awaisi University of Birmingham, UK Imaging the beating heart: Real-time visualisation of microvascular thrombo-inflammation Richard Southworth King's College London, UK Development and application of novel imaging tools capable of non-invasive detection of tissue hypoxia and mitochondrial injury Selected Abstracts: (15 minutes each) O19 - Jake Burke Imperial College London, UK L-type calcium channel regulation by β2AR in a co-culture model of innervated cardiomyocytes O20 - Sasha Forbes University of Glasgow, UK Cardiac regenerative cell therapy: An integrative optical approach to investigate early electrical coupling in an isolated rabbit heart Session Chairs: Andrew Holmes University of Birmingham, UK Yann Jamin, Scintica, Canada |
Session 11 - Inter-organ Crosstalk in Cardiometabolic Diseases Invited Speakers: (20 minutes each) David Paterson, University of Oxford, UK Neural mediators in cardiovascular disease Alexandre Paccalet, University of Lyon, France Bone marrow niche and the heart Ulrich Kintscher, Charite Universitätsmedizin Berlin, Germany Adipose tissue-heart crosstalk Selected Abstracts: (15 minutes each) O21 - Lorenza Koppers, Imperial College London, UK Investigating the effect of cardiac macrophages on contractility in human donor and failing living myocardial slices O22 - Meg Potter, Heidelberg University Clinic, Germany Adipose based interorgan communication in the context of obesity, myocardial infarction and cardiac remodelling Session Chairs: Rebecca Ritchie, Monash University, Australia Alice Marino, UCLouvain, Belgium |
Session 12 - Hot Topics in HFpEF Invited Speakers: (20 minutes each) Christophe Beauloye, UCLouvain, Belgium Cardiac and plasma metabolic signatures in HFpEF Francesco Paneni, University of Zurich and Zurich University Hospital, Switzerland Epigenetics in cardiometabolic diseases Gabriele Schiattarella, German Heart Center of the Charité, Germany Selected Abstracts: (15 minutes each) O23 - Miguel Mano, University of Coimbra, Portugal MicroRNA-mediated control of cardiac fibrosis: unravelingkey regulators and mechanisms through functional genomics screenings O24 - Bernadin Ndongson Dongmo, Oslo University Hospital, Norway Gene therapy with Phosphodiesterase 2A overexpression prevents atrial fibrillation and conduction dysfunction independently of diastolic dysfunction in a mouse HFpEF model Session Chairs: Nazha Hamdani, Ruhr University Bochum, Germany Simon Sedej, Medical University of Graz, Austria |
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| 15:00 - 16:30 | Refreshment Break and Poster Session 3 - (M208/M209) | |||
| 16:30 - 18:00 |
Session 13 - Multimodal Approaches to Explore Cardiac Diseases Invited Speakers: (20 minutes each) Ming Lei, University of Oxford, UK Targetting Pak-1 as a new therapy for cardiac disease Alicia Lundby, University of Copenhagen, Denmark Unraveling cardiac arrhythmias through proteomics Javier Barallobre-Barreiro, Imperial College London, UK Omics to decipher molecular heterogeneity in HF Selected Abstracts: (15 minutes each) O25 - Emma Zanella, University of Padova, Italy Multicellular human cardiac microtissues to uncover disease mechanisms and therapeutic rescue in arrhythmogenic cardiomyopathy O26 - Alessia Virzì, KUL, Leuven, Belgium Uncovering the molecular and cellular basis of cardiac recovery of the failing heart after mechanical unloading Session Chairs: Yoshihiko Saito, Nara Medi-cal University, Japan Monika Gladka, University Medical Center Amsterdam, Netherlands |
Session 14 - Vascular Integrity and Dysfunction in Heart Failure Invited Speakers: (20 minutes each) Elizabeth Jones, KU Leuven, Belgium Mural cell dysfunction contributes to diastolic heart failure Marie-Ange Renault, UMR Inserm U1034, France Endothelial dysfunction in HFpEF Paola Cattaneo, University of Milan, Italy Discovering novel targets to control cardiac fibrosis Selected Abstracts: (15 minutes each) O27 - Nicoletta Bartoloni, University Of Trieste, Italy Mechanical load controls vascular integrity in the heart O28 - Jialu Li, University of Bristol, UK Endothelial heparan sulphate deficiency impairs cardiac function and post–ischemia–reperfusion recovery Session Chairs: Asif Iqbal, University of Birmingham, UK Manuel Mayr, Imperial College London, UK |
Session 15 - Alteration of Iron Homeostasis and Ferroptosis in Cardiac Disease Invited Speakers: (20 minutes each) Samira Lakhal-Littleton, University of Oxford, UK Alteration of myocardial iron homeostasis in heart failure Frank Lezoualc’h, University of Toulouse, France Epac1, a novel iron metabolic sensor Asa Gustafsson, University of Padova, Italy Cardiac Mitochondria Under Surveillance: ATG9A and Quality Control Selected Abstracts: (15 minutes each) O29 - Ilias Simon, Institute of metabolic and cardiovascular diseases, INSERM, France Impaired lysosomal iron supply to mitochondria drives cardiomyocyte senescence in the aging heart O30 - Alejandro Ciocci Pardo, University of Padua, Italy Presenilin-2 Is a key molecule in Cardiac SR–Mitochondria Architecture and Metabolic Homeostasis Session Chairs: Luc Bertrand, Uclouvain, Belgium Jonathan Lambert, University of Padova, Italy |
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| From 19:00 | Conference Gala Dinner - Council House, Birmingham City Centre | |||
As part of the organisation of this conference, The University of Birmingham's Event Management Team is collecting income via registration fees and sponsorships on behalf of theInternational Society for Heart Research, European Section (ISHR-ES)