| Time | Session/Location | |||
|---|---|---|---|---|
| 07:00 - 09:00 | ES-ISHR council meeting - Room 202 |
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| 08:00 - 09:00 | Registration and Refreshments - Foyers of Teaching and Learning Building |
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| 09:00 - 10:00 |
Plenary session 2 - Lecture Theatre 1 Gianluigi Condorelli (Humanitas University, Italy) Ketty Schwartz Award Lecture |
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| 10:00 - 10:30 | Refreshment Break - Foyers of Teaching and Learning Building | |||
| Lecture Theatre 1 - Teaching and Learning Building |
Lecture Theatre 2 - Teaching and Learning Building |
G15 - Muirhead Tower |
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| 10:30 - 12:00 | Session 7 - Determinants of the Interorgan Crosstalk Invited Speakers: (20 minutes each) Carolina Greco Circadian mechanisms Roger Foo Cardiovascular, Kidney, Liver, and Metabolic Interactions in Heart Failure: Breaking Down Silos Genevieve Derumeaux Aging at the Crossroads of Organ Interactions: Implications for the Heart Selected Abstracts: (15 minutes each) Abbie Hayes Renal dysfunction induces early atrial electrophysiological remodelling independent of hypertension and ventricular structural disease: partial reversal by SGLT2 inhibition Tania Zaglia Neonatal Sympathetic Denervation Prevents Disease Manifestation in Desmoglein-2–linked Arrhythmogenic Cardiomyopathy Session Chairs: Melanie Paillard Gabriele Schiattarella |
Session 8 - From Epigenetics to Precision Targets Invited Speakers: (20 minutes each) Nadia Mercader Paternal cardiac lesion induces cardiac metabolic adaptation in offspring Susana P Pereira Maternal Programming of Offspring Cardiovascular Function Llew Roderick Epigenetics in heart failure Selected Abstracts: (15 minutes each) Azra Husetić Exploring the Role of Calcineurin A in Cardiomyocyte Cell Cycle Re-entry for Post-injury Regeneration Parul Gupta Zeb1-Dependent Transcriptional Programs Underlie Female-Biased Cardiac Dysfunction Session Chair: Ralf Gilsbach |
Session 9 - Proteostasis in Heart Failure Invited Speakers: (20 minutes each) Zhao Wang Role of protein turnover in heart failure Izhak Keha Subcellular protein translation in HF Mirko Völkers Protein translation control Selected Abstracts: (15 minutes each) Maya Noureddine Mechanistic insights into an α-actinin-2 variant: Linking functional impairment to biophysical alterations in hypertrophic cardiomyopathy TBC Session Chairs: Manuel Mayr Lucie Carier |
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| 12:00 - 13:30 | Lunch and Poster Session 2 | |||
| Lecture Theatre 1 - Teaching and Learning Building |
Lecture Theatre 2 - Teaching and Learning Building |
G15 - Muirhead Tower |
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| 13:30 - 15:00 |
Session 10 - Scintica Sponsored Session TBD - Imaging Across Scales in Cardiovascular Research Invited Speakers: (20 minutes each) Mona Malek Mohammadi New frontiers in cardiac regeneration Juma el-Awaisi TBC Richard Southworth Development and application of novel imaging tools capable of non-invasive detection of tissue hypoxia and mitochondrial injury Selected Abstracts: (15 minutes each) Jake Burke L-type calcium channel regulation by β2AR in a co-culture model of innervated cardiomyocytes Selected Abstract TBC Sasha Forbes Cardiac regenerative cell therapy: An integrative optical approach to investigate early electrical coupling in an isolated rabbit heart Session Chairs: Andrew Holmes TBC |
Session 11 - Inter-organ Crosstalk in Cardiometabolic Diseases Invited Speakers: (20 minutes each) David Patterson Neural mediators in cardiovascular disease Alexandre Paccalet Bone marrow niche and the heart Ulrich Kintscher Adipose tissue-heart crosstalk Selected Abstracts: (15 minutes each) Lorenza Koppers Investigating the effect of cardiac macrophages on contractility in human donor and failing living myocardial slices TBC Session Chairs: Rebecca Ritchie Alice Marino |
Session 12 - Hot Topics in HFpEF Invited Speakers: (20 minutes each) Christophe Beauloye Cardiac and plasma metabolic signatures in HFpEF Francesco Paneni Epigenetics in cardiometabolic diseases Claudia Crocini Fibrosis in HFpEF pathogenesis Selected Abstracts: (15 minutes each) Miguel Mano MicroRNA-mediated control of cardiac fibrosis: unravelingkey regulators and mechanisms through functional genomics screenings Bernadin Ndongson Dongmo Gene therapy with Phosphodiesterase 2A overexpression prevents atrial fibrillation and conduction dysfunction independently of diastolic dysfunction in a mouse HFpEF model Session Chairs: Nazha Hamdani Simon Sedej |
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| 15:00 - 16:30 | Refreshment Break and Poster Session 3 | |||
| 16:30 - 18:00 |
Session 13 - Multimodal Approaches to Explore Cardiac Diseases Invited Speakers: (20 minutes each) Ming Lei Targetting Pak-1 as a new therapy for cardiac disease Alicia Lundby Unraveling cardiac arrhythmias through proteomics Javier Barallobre-Barreiro Omics to decipher molecular heterogeneity in HF Selected Abstracts: (15 minutes each) Emma Zanella Multicellular human cardiac microtissues to uncover disease mechanisms and therapeutic rescue in arrhythmogenic cardiomyopathy Alessia Virzì Uncovering the molecular and cellular basis of cardiac recovery of the failing heart after mechanical unloading Session Chairs: Yoshihiko Saito Monika Gladka |
Session 14 - Vascular Integrity and Dysfunction in Heart Failure Invited Speakers: (20 minutes each) Elizabeth Jones Mural cell dysfunction contributes to diastolic heart failure Marie-Ange Renault Endothelial dysfunction in HFpEF Paola Cattaneo Discovering novel targets to control cardiac fibrosis Selected Abstracts: (15 minutes each) Nicoletta Bartoloni Mechanical load controls vascular integrity in the heart Jialu Li Endothelial heparan sulphate deficiency impairs cardiac function and post–ischemia–reperfusion recovery Session Chairs: Asif Iqbal Petra Kleinbongard |
Session 15 - Alteration of Iron Homeostasis and Ferroptosis in Cardiac Disease Invited Speakers: (20 minutes each) Samira Lakhal-Littleton Alteration of myocardial iron homeostasis in heart failure Frank Lezoualc’h Epac1, a novel iron metabolic sensor TBC Selected Abstracts: (15 minutes each) Ilias Simon Impaired lysosomal iron supply to mitochondria drives cardiomyocyte senescence in the aging heart Alejandro Ciocci Pardo Presenilin-2 Is a key molecule in Cardiac SR–Mitochondria Architecture and Metabolic Homeostasis Session Chairs: Luc Bertrand Jonathan Lambert |
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| From 19:00 | Conference Gala Dinner - Council House, Birmingham City Centre | |||
As part of the organisation of this conference, The University of Birmingham's Event Management Team is collecting income via registration fees and sponsorships on behalf of theInternational Society for Heart Research, European Section (ISHR-ES)