Thursday 25 June 2025

Time	Session/Location
08:30 - 09:30	ISHR-INT Council Meeting - Room 202
08:30 - 09:30	Registration and Refreshments - Foyers of Teaching and Learning Building
9:30 - 10:30	Plenary Session 4 - Lecture Theatre 1 ECI Awards Session Giulio Ciucci Mechanical Loading Inhibits Tumor Growth in the Heart Thomas Wright NLRP3 inhibition reduces myocardial infarction in the context of cardiorenal disease Sara Rega Patient-derived decellularized aortas are a novel advanced 3D in vitro platform for the study of aortopathies Jonathan Lambert Defining metabolically dependent protein interactomes of Opa1 in cardiac mitochondria using a novel Opa1-TurboID transgenic mouse model Ravi Kumar Improving the physiological relevance of hIPSC-CM with human-serum mimetic culture media
10:30 - 11:00	Refreshment Break - Foyers of Teaching and Learning Building
	Lecture Theatre 1 - Teaching and Learning Building	Lecture Theatre 2 - Teaching and Learning Building	G15 - Muirhead Tower
11:00 - 12:30	Session 22 - New AI and Tools to Explore Cardiac Diseases (JMCC sponsored session Invited Speakers: (20 minutes each) Christoph Dieterich How AI & bioinformatics can help in cardiovascular research Jeff Saucerman Logic-based machine learning to predict how drugs affect cardiomyocyte hypertrophy Xin Zhou Computational cardiac imaging and the UK Biobank Selected Abstracts: (15 minutes each) Helen Maddock Predictive Outcome Of A Blinded Cardiovascular Pre-clinical Screening Evaluation (In-silico and In-vitro) for Use as a Cardiovascular Safety Triage For Drug Discovery Izzatullo Sobitov Distinct Functional Signatures in Atrial and Ventricular HumaniPSC-derived Cardiomyocytes Revealed by High-Throughput Assays Session Chairs: Bianca Brundel	Session 23 - Lipids Signalling in Cardiac Metabolism and Cardiac Failure Invited Speakers: (20 minutes each) Frederic Boal Phosphoinositides, PIKfyve, lysosomal function and cardiac metabolism Marion Laudette PCSK9, mitochondrial cholesterol, metabolism Claudio Mauro Memory of obesity in adaptive immunity Selected Abstracts: (15 minutes each) Xin Hu Exogenous lactate/pyruvate reduces the hypertrophic driver aspartate through reducing carbohydrate oxidation and pyruvate carboxylation in the ex vivo heart Kaitlyn Dennis The influence of dietary fat composition on hepatic fat metabolism: findings from in vivo human and in vitro cellular models Session Chairs: Federica Cuello Yu Huang	Session 24 - Therapeutic Targeting to Enhance Cardioprotection Invited Speakers: (20 minutes each) Ludovic Gomez Serine 663 phosphorylation of SERCA2 in cardiac disease Xiaoqiu Tan Targeting pak2 as a novel therapy for cardiac diseases Neena Kalia Targeting microcirculation in cardiovascular disease Selected Abstracts: (15 minutes each) Ying-Chi Chao Targeting Troponin I Phosphorylation for Precision Treatment of Diastolic Dysfunction Isotta Chimenti Photo-thermal activation–induced killing of gold nanorod–loaded human cardiac fibroblasts Session Chairs: Julie McMullen Sean Davidson
12:30 - 13:15	Plenary session 5 - Lecture Theatre 1 ES-Awards - Poster and Young Investigator awards
13:10 - 14:30	Lunch - Foyers of Teaching and Learning Building
From 14:30	Departure