| Time | Session/Location | |||||||||||||||||||
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| 07:00 - 09:00 | ES-ISHR Council Meeting - Room 202 | |||||||||||||||||||
| 08:30 - 09:00 | Registration and Refreshments - Foyers of Teaching and Learning Building | |||||||||||||||||||
| 09:00 - 10:30 | Young Investigator Session 1 (JMCC sponsored) - Lecture Theatre 1 Flash Talks (3 minutes each) Yannik Andrasch Immune-myocardial crosstalk in cardiomyocyte polyploidization Aurelien Barthou The RIα subunit of PKA forms biomolecular condensates and controls cAMP/PKA signaling in cardiomyocytes Angeliki Choustoulaki Chronic exposure to wild type and mutant transthyretin induces cardiotoxicity in primary murine cardiomyocytes via downregulation of OXPHOS complexes Angeline Geiser The Myo-Inositol/SMIT1 Axis as a Key Regulator of Heart Failure and Cardiac Fibrosis Jack Antoine Gemayel Intracardiac Ganglia, a Specialized Niche for Cardiac Telocytes: Targeted Isolation and Functional Calcium Signaling Characterization Maxime Gouin-Gravezat Mitochondrial NO signalling, a key regulator of cardiac response to adrenergic stress Zsombor I. Hegedus Divergent Roles of ICOS and ICOSL in Cardiac Fibrosis and Ventricular Remodelling Or Levi Cardiomyocyte-Specific Disruption of the AKAP6β -RSK3 Signalosome Attenuates Implant-Induced Susceptibility to Atrial Fibrillation in Rats Merel Lianne Ligtermoet ZEB2 Overexpression Preserves Cardiac Function in a TPM1-E54K Mouse Model of Genetic Dilated Cardiomyopathy Aiste Liutkute Persistent Atrial Fibrillation Is Associated with Proteome Profile Homogenization Between Left and Right Atria Molly O'Reilly (Para)sympathetic nervous system remodeling in CPVT: functional implications for cardiac autonomic regulation Jiabin Qin Unravelling the role and mechanisms of SK4 channels in atrial fibrillation: the immune-cardiac crosstalk Katie Tompkins Sympathetic Nervous System Dysregulation and Ventricular Arrhythmogenesis in a Progressive Murine Model of Chronic Kidney Disease Nuha Yeniturkogullari Proteoglycan remodelling in human cardiac development Sejal Singal Nav1.5 clustering at the neuro-cardiac junction by an Ankyrin-G-dependent mechanism is required for sympathetic control of cardiomyocytes Freddy Ganse From Nanotherapy to Thermal Conditioning: Novel Approaches to Blunt Air Pollution–Induced Arrhythmias |
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| 10:30 - 11:00 | Refreshment Break | |||||||||||||||||||
| 11:00 - 12:30 | Young Investigator Session 2 - Lecture Theatre 1 | |||||||||||||||||||
| 12:30 - 13:30 | Poster Display and Lunch | |||||||||||||||||||
| 13:30 - 14:00 |
Opening Ceremony - Lecture Theatre 1 Prof Adam Tickell (Vice chancellor of University of Birmingham) |
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| 14:00 - 15:00 |
Plenary Session 1 - Lecture Theatre 1 Prof Barbara Casadei (Imperial College London) |
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| Lecture Theatre 1 - Teaching and Learning Building |
Lecture Theatre 2 - Teaching and Learning Building |
G15 - Muirhead Tower |
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| 15:00 - 16:30 | Session 1 - Battle of the Metabolites: Should we focus on glucose, fats, or ketones? (JMCC sponsored) Invited Speakers: (20 minutes each) Luc Bertrand Glucose-derived metabolites in heart failure Michael Shattock Beyond Glucose: Metabolic substrate provision for a healthy heartenergetics, function and stability ex vivo Anna Zoccarato Intermediary Metabolism in Cardiac Remodelling Selected Abstracts: (15 minutes each) Eliano dos Santos PGAM2 is a critical metabolic node in heart failure progression Xi QI Mitofusin 2 Deficiency Causes Atrial Lipid Accumulation in Experimental and Human Atrial Fibrillation and Diabetes Mellitus Session Chairs: Lisa Heather Lorrie Kirshenbaum |
Session 2 - Inflammation and Immunity in Cardiac Remodelling Invited Speakers: (20 minutes each) Federica Marelli-Berg T cells in cardiac health and disease Ziad Mallat Macrophages inflammasome & mitochondrial homeostasis Gustavo Ramos Immune regulation as a therapeutic approach Selected Abstracts: (15 minutes each) Jack Keane The role of tissue resident memory T cells in atrial fibrillation Ingrid Dumitriu Immune remodelling in atrial fibrillation: are alterations in inflammatory T cell subsets the missing link? Session Chairs: Ines Falcao-Pires Marinos Kallikourdis |
Session 3 - The dynamics of epi-genome/transcriptome in cardiac remodelling Invited Speakers: (20 minutes each) Sebastian Preissl Epigenetic mechanisms at single cell resolution Fabio Martelli Non-coding RNAs in ischemic cardiovascular disease Eva van Rooij Creating a repair permissive heart Selected Abstracts: (15 minutes each) TBC TBC Session Chairs: Llew Roderick Miron Sopic |
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| 16:30 - 18:00 | Refreshments and Poster Session 1 | |||||||||||||||||||
| 17:00 - 18:00 | IMAGINE+ networking event - Lecture Theatre 2 | |||||||||||||||||||
| Lecture Theatre 1 - Teaching and Learning Building |
Lecture Theatre 2 - Teaching and Learning Building |
G15 - Muirhead Tower |
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| 18:00 - 19:30 |
Session 4 - AZ sponsored session - Cardiovascular, Renal and Metabolic diseases at crossroads
Invited Speakers: (20 minutes each) Don Bers Obese-diabetic HFpEF: Sex, EC-Coupling and Empagliflozin Elise Kesler Talk Title TBC TBC Selected Abstracts: (15 minutes each) Lukas Emanuel Schmidt Proteomic Effects of Genetic and Therapeutic PCSK9 Inhibition Milena Bellin In Vitro Modelling of Renal Injury-Induced Cardiac Dysfunction Using hiPSC-Derived Kidney Organoids and Cardiac Microtissues Session Chairs: Elie Kessler Thomas Eschenhagen |
Session 5 - Cardiac Regeneration: Lessons from development and beyond
Invited Speakers: (20 minutes each) Filipa Simoes Role of macrophages in cardiac regeneration Stephane Zaffran (De)constructing the human heart: single-cell/nucleus insights Monika Gladka Cardiac regeneration and rejuvenation mechanisms Selected Abstracts: (15 minutes each) Matteo Riccio Regulation of cardiomyocyte proliferation by tropomyosin-dependent sarcomeric structure Ilaria Luciana Carlotta Del Giudice Age-Dependent Lumican Remodelling Limits Cardiac Angiogenesis After Birth Session Chairs: Sveva Bollini Mauro Giacca |
Session 6 - Preventing cancer-derived cardiotoxicity
Invited Speakers: (20 minutes each) Zoltán V. Varga Effect of immune checkpoint inhibitors on cardiac function Alessandra Ghigo Adjuvant cardiotherapy: SGLT2i, GLP1R agonists and beyond TBC Selected Abstracts: (15 minutes each) Giulia Guerra Hemopexin mitigates doxorubicin cardiotoxicity by preserving cardiac metabolism while maintaining antitumor efficacy in a mouse model of breast cancer TBC Session Chairs: Jolanda van der Velden Gabriele Tocchetti |
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| 19:30 - 20:30 | Drinks Reception with Nibbles - Teaching and Learning Building Foyers | |||||||||||||||||||
As part of the organisation of this conference, The University of Birmingham's Event Management Team is collecting income via registration fees and sponsorships on behalf of theInternational Society for Heart Research, European Section (ISHR-ES)