MEMTAB 2025

Conference Programme

Tuesday 29th April: Pre-conference courses (prebookings only)

Murray Learning Centre

Course 1 - Room UG06	An Introduction to Clinical Prediction Models and Sample Size Calculations for Model Development & Evaluation Faculty includes: Dr. Joie Ensor, Dr. Kym Snell, Dr. Lucinda Archer, Dr Rebecca Whittle, Dr. Amardeep Legha and Prof. Richard Riley from University of Birmingham
9:30 - 10:00	Registration and Refreshments
10:00 - 17:00	Course – including lunch
Course 2 -Room UG07	Systematic Reviews of Prognosis Studies Faculty includes: Dr. Anneke Damen, Prof. Carl Moons from UMC Utrecht
9:30 - 10:00	Registration and Refreshments
10:00 - 17:00	Course – including lunch
Course 3 - Room UG09	The Potential and Pitfalls of Predicting Treatment Effects Faculty includes: Prof. David M. Kent from Tufts Medical Center Dr. David Van Klaveren, Erasmus MC University Medical Center
12:30 - 13:00	Registration and Refreshments
13:00 - 17:00	Course – including lunch

18:30 - 20:00

Welcome Reception
Drinks and canapes
Lloyd Suite, Edgbaston Park Hotel

Wednesday 30th April - Conference Day 1

Alan Walters Building (Lecture Theatre 1 & Posters & Refreshments) and Muirhead Tower (Lecture Theatre 2)

Please note that all plenary sessions in Lecture Theatre 1 will also be streamed into an adjacent room (on Level 1) if you would prefer a more spacious environment.

8:30 - 9:30	Registration and Refreshment
9:30 - 9:40	Welcome and Introduction (Richard Riley) - Lecture Theatre 1 (Alan Walters)
9:40 - 10:25	Session 1: S1. Methodology that stands the test Patrick M Bossuyt, Professor of Clinical Epidemiology, University of Amsterdam Chaired by Richard Riley - Lecture Theatre 1 (Alan Walters)
10:25 - 11:00	Break
	Session 2: Methodology for models, tests and biomarkers
	Tests Chaired by Jac Dinnes Lecture Theatre 1 (Alan Walters)	Predictions Chaired by Lucinda Archer Lecture Theatre 2 (Muirhead Tower)
11:00 - 11:15	O1. QUADAS-3: updated tool to evaluate risk of bias and applicability concerns in diagnostic test accuracy studies Penny Whiting, University of Bristol	O6. Performance evaluation of predictive AI models to support medical decisions: overview and guidance Ben Van Calster, KU Leuven
11:15 - 11:30	O2. What is the evidence base for claims of accuracy for rapid self-test diagnostics sold in UK retail settings? Beth Hillier, University of Birmingham	O7. A software implementation for sample size calculation targeting precise risk predictions Joie Ensor, University of Birmingham
11:30 - 11:45	O3. Research Waste in Evidence Synthesis for Health Population Screening: A Systematic Review Sarah Batson, University of Warwick	O8. Developing a clinical prediction model with a continuous outcome: sample size calculations to target precise predictions Rebecca Whittle, University of Birmingham
11:45 - 12:00	O4. Bayesian statistical methods for diagnostic studies that allow early termination for futility Jordan Oakley, Newcastle University	O9. Adapting sample size calculations for the development of prediction models to control for model stability Menelaos Pavlou, University College London
12:00 - 12:15	O5. Opportunities to speed up in-vitro diagnostic adoption and patient access in the UK: the pre-eclampsia testing timeline Katie Scandrett, University of Birmingham	O10. How to Handle Missing Data across the Development, Validation and Implementation of Clinical Prediction Models Glen Martin, University of Manchester
12:15 - 13:15	Lunch and Networking
13:15 - 13:55	Session 3: S2. Value of information analysis: towards a value-based approach in biomarker and prediction model research Mohsen Sadatsafavi, Associate Professor, University of British Columbia Chaired by Joie Ensor - Lecture Theatre 1 (Alan Walters)
13:55 - 14:05	Break
	Session 4: Methodology for models, tests and biomarkers
	Tests Chaired by Hans Reitsma Lecture Theatre 1 (Alan Walters)	Prediction Chaired by Carl Moons Lecture Theatre 2 (Muirhead Tower)
14:05 - 14:20	O11. Simulation Study Examining Impact of Study Design Factors on Variability Measures Laura Quinn, University of Birmingham	O16. Value-of-Information Analysis for External Validation of Risk Prediction Models in Multicenter Studies and Systematic Reviews Laure Wynants, Maastricht University
14:20 - 14:35	O12. Real world implementation of the Biomarker Toolkit: a Tool aiming to quantifiably assess biomarker utility and guide development Katerina-Vanessa Savva, Imperial College London	O17. Comparing Performance of Methods that Correct for Data Distribution Shift when Developing Clinical Prediction Models: A Simulation Study Haya Elayan, University of Manchester
14:35 - 14:50	O13. Methodology to create evidence-based testing panels for monitoring long-term conditions in primary care Martha Elwenspoek, University of Bristol	O18. Use of statistical process control to monitor calibration-in-the-large of a clinical prediction model David Jenkins, University of Manchester
14:50 - 15:05	O14. Measurement Error: Unlocking Estimates of Test Variability From Routine Data. Methods for Statistical Analysis and a Case-Study Series Simon Baldwin, University of Birmingham	O19. Combining calibration plots from multiple centers or datasets Lasai Barreñada, KU Leuven
15:05 - 15:20	O15. Evaluation of diagnostic tests with spatially or temporally clustered data, part 1: The choice of estimands and estimators affects results and interpretation Nicole Rübsamen, University of Münster	O20. Network meta-analysis of prediction models using aggregate or individual participant data - A scoping review and recommendations for reporting and conduct Maerziya Yusufujiang, UMC Utrecht
15:20 - 16:15	Break and Poster Viewings - Room G11 (Alan Walters)
	Session 5: Patient and Public Involvement & Engagement Chaired by Kym Snell - Lecture Theatre 1 (Alan Walters)
16:15 - 16:30 16:30 - 16:45 16:45 - 17:00	S3. The need for PPIE within methodology research Laura Gray, Biostatistics Research Group, University of Leicester S4. Experiences of a PPIE representative within methodology research Emily Lam, PPIE Representative S5. Establishing and working with PPIE panels from prediction model research: what we have learnt Paula Dhiman, Senior Research in Medical Statistics, University of Oxford
17:00 - 17:15	Close - Lecture Theatre 1 (Alan Walters)

19:00 - til' late

Conference Dinner (prebooked tickets only)
Council House, Birmingham

Thursday 1st May - Conference Day 2

Alan Walters Building (Lecture Theatre 1 & Posters & Refreshments) and Muirhead Tower (Lecture Theatre 2)

8:30 - 9:00	Registration and Refreshments
9:00 - 9:05	Welcome to Day 2 - Lecture Theatre 1 (Alan Walters)
9:05 - 9:50	Session 6: S7. Are AI-enabled systems in healthcare fit for purpose? Toward equitable, fair and trustworthy systems for disease detection and risk prediction Alicja Rudnicka, Professor of Statistical Epidemiology in the Population Health Research Institute, City St Georges, University of London Chaired by Joie Ensor - Lecture Theatre 1 (Alan Walters)
9:50 - 10:45	Break and Poster Viewings - Room G11 (Alan Walters)
	Session 7: Methodology for models, tests and biomarkers
	Tests Chaired by Rafael Perera Lecture Theatre 1 (Alan Walters)	Prediction Chaired by Paula Dhiman Lecture Theatre 2 (Muirhead Tower)
10:45 - 11:00	O21. Evaluating Diagnostic Tests Against Composite Reference Standards: Quantifying and Adjusting for Bias Vera Hudak, University of Bristol	O27. PROBAST+AI: An updated quality, risk of bias and applicability assessment tool for prediction models using regression or artificial intelligence methods Anneke Damen, UMC Utrecht
11:00 - 11:15	O22. Improving the reference standard in diagnostic accuracy studies: Evaluating a latent class model against a panel of expert clinicians Tom Parry, University College London	O28. Guidance for unbiased predictive information for healthcare decision-making and equity (GUIDE): considerations when race may be a prognostic factor David Kent, Tufts Medical Center
11:15 - 11:30	O23. Examining the Association between Estimated Prevalence and Diagnostic Test Accuracy Using Directed Acyclic Graphs Yang Lu, McGill University	O29. A simulation study investigating the impact of the prediction paradox on clinical prediction model performance Samantha Pacynko, University of Manchester
11:30 - 11:45	O24. Diagnostic accuracy of tests for SARS-CoV-2 acute infection: Distinguishing measurands from target conditions Joanna Merckx, McGill University	O30. CHARIOT: A prediction-under-intervention model for cardiovascular primary prevention Matthew Sperrin, University of Manchester
11:45 - 12:00	O25. The estimand framework for diagnostic accuracy studies Antonia Zapf, University Medical Center Hamburg-eppendorf	O31. Stronger penalties on treatment-covariate interactions improve treatment effect predictions and prevent potential treatment mistargeting David Van Klaveren, Erasmus MC
12:00 - 12:15	O26. How do authors of comparative accuracy studies analyse data when reporting a comparative conclusion: methodological review? Yaxin Chen, Amsterdam UMC	O32. Effects of Using Natural Language Processing for Cohort Selection from Electronic Health Records on Subsequent Prognostic Prediction Model Performance Isa Spiero, UMC Utrecht
12:15 - 13:15	Lunch and Networking
13:15 - 13:50	Session 8 : S8. Performance Evaluation of Diagnostics - Industry Challenges and Opportunities for Regulatory Science Mike Messenger, BIVDA Chaired by Clare Davenport - Lecture Theatre 1 (Alan Walters)
13:50 - 14:00	Break
	Session 9: Regulation of Tests and Models Chaired by Niels Peek - Lecture Theatre 1 (Alan Walters)
14:00 - 14:15 14:15 - 14:30 14:30 - 14:45 14:45 - 15:00	O33. Identifying Priority Areas for Target Product Profile Development in Early Cancer Diagnostics Bethany Shinkins, University of Warwick/ NICE O34. Developing diagnostic target product profiles for managing infections and exacerbations in cystic fibrosis: a sequential mixed-methods design. Nicola Howe, Newcastle University O35. Lost in Translation: The Current and Future Regulatory Landscape as an Often-Overlooked Hurdle for Impact in Clinical Prediction Models Benjamin Perry, University of Birmingham O36. Assessment of Prediction Models in Europe: Gaps in Evidence Requirements Tuba Saygin Avsar, NICE
15:00 - 15:40	Break
15:40 - 16:40	Session 10: Standing The Test For The Future Chaired by Richard Riley - Lecture Theatre 1 (Alan Walters) Panel: Jon Deeks, Rishi Gupta, Anne de Hond, Chris Hyde, Mariska Leeflang, Sowmiya Moorthie
16:40 - 17:00	Awards and Closing Remarks - Lecture Theatre 1 (Alan Walters)