POSTER PRESENTATIONS

Thursday 11th September

P1	Chongluan Shi - Investigating the regulation of E3 ubiquitin ligase TRAIP in DNA replication
P3	Jemma Holland - Genomic profiling of oncohistone H4R3C and its links to genome instability
P5	Gemma Regan-Mochrie - Histone H4R3C: A New Oncohistone that Drives Genomic Instability
P7	Erik Soderback - Covaris truCOVER Library Prep: A Streamlined WGS Workflow for Enhanced NGS Library Performance and Data Quality
P9	Alice Ormrod - The radiobiological impact of protons in combination with DNA double strand break repair inhibitors in glioblastoma models
P11	Abby Gardner - Investigating the impact of NELF-C on transcriptional dynamics and nuclear features
P13	Rosa Camarillo Daza - The where, when and how of DNA repair in quiescent cells
P15	Rachel Bayley - Using in vitro stem cell models to study the biology of fusion genes during embryonic haematopoiesis
P17	Panagiotis Kotsantis - RNF169 is implicated in the DNA replication stress response
P19	Edward Brown - The Structure of the core SMRT Complex
P21	Elizabeth Anthony and Ruth Densham - Using a BRCA1/BARD1 gap-suppression separation of function mutant to elucidate mechanisms of therapy responses
P23	Ciara Ward - Understanding the role of PRMT5 in the DNA damage response in MTAP-deficient lung cancer cells
P25	Maryam Eftekharifar - Deciphering cell-type specific inter-chromosomal genome architecture via single-cell Hi-C and machine learning
P27	Sahar Shahidkalhori - The role of UPF1 in transcription and translation in eukaryotic cells
P29	Tom Wright - Combining Genome Engineering with Next-Generation Sequencing to Unravel the Functions of the NuRD Complex
P31	Gina Rose - X Inactivation In Lymphocytes and Systemic Lupus Erythematosus
P33	Yagiz Ozturk - Ctdp1, a phosphatase at the intersection of transcription and cell viability
P35	Cristina Tufarelli - Profiling molecular changes driven by dietary substances in healthy and cancer colon epithelial cells
P37	Alexander Lanz - SUMOylation promotes mitotic DNA damage repair
P39	Akhil Bowry - The 7SK small nuclear ribonucleoprotein marries the cell responses to both transcriptional and replication stress by promoting homologous recombination and replication fork reversal
P41	Poppy Conway-Thomas - Uncovering the roles of the peptidyl prolyl isomerase PIN1 in the replication stress response
P43	Panagiotis Patsis - Dissecting the regulatory mechanisms of the histone H3 lysine 9 methyltransferase Clr4
P45	Yutong Liang - Role of the BPTF subunit of the NURF chromatin remodelling enzyme in melanoma
P47	Alice Victory - Investigating the role of HDAC3 in human embryonic development
P49	Thomas Strange - Investigation of KRAS mutation effects on transcription and genomic integrity

Friday 12th September

P2	Mona Elmokadem - The role of Protein protein interactions in DNA double strand break in chromatin
P4	Alkisti Manousaki - Unravelling Mechanistic Insights Between X-Chromosome Inactivation Dysregulation and Female-Biased Mitochondrial Dysfunction Underlying Autoimmunity
P6	Nagham Ghaddar - The impact of the SWI/SNF complex subunit ARID1A on the chromatin environment surrounding stalled replication forks
P8	David Barnes - An expanded repertoire of germline variants in known cancer predisposition genes are predicted to be pathogenic by machine learning in childhood and TYA cancers
P10	Eduardo De La Vega - Unbiased detection of replication initiation events in human cells using BrdU incorporation and single-molecule nanopore sequencing
P12	AlAnood Waslullah AlHjajji - Structural and Chemical Biology Investigations of Benzamide-Derived PROTACs for Class I Histone Deacetylase Ubiquitination and Proteasome-Mediated Degradation in HCT116 Cells
P14	Maria Rita Fabbrizi - Understanding the cellular DNA damage response in head and neck cancer cells treated with Boron Neutron Capture Therapy
P16	Raul Sanchez Pastor - Randomised control generation for Hi-C analysis by data distribution extrapolation
P18	Emily Prowse - Inhibition of PRMT5-mediated arginine methylation decreases Ewing sarcoma (ES) survival in an EWSR1-ETS-dependent manner by inducing DNA damage
P20	Oksana Gonchar - Endogenous Purification and Structural Characterization of the NuRD Corepressor Complex Using CRISPR Knock-In in HEK293F Cells
P22	Olga Brieieva - The lysine methyltransferase SETD1A promotes ssDNA gaps formation under replication stress
P24	Kristupas Sirvydis - XIST supercomplexes- key actors in X-inactivation during early human embryonic development
P26	Csilla Varnai - Identifying inter-chromosomal transcription regulatory networks from the 3D genome
P28	Ammarah Tariq - Structure and Regulation of the H2B E3 Ligase Complex
P30	Eve Day - A single cell RNA-seq analysis into Immunoglobulin expression and potential function in AML myeloblasts
P32	Paolo Passaretti - The Structure of the Xenopus laevis Replisome
P34	Anna Devari - Uncovering the molecular stoichiometries of transcriptional silencing in X-inactivation
P36	Rosanna Wilkins - Upregulation of human RNase H2 counteracts replication stress elicited by oncogenes and chemotherapy drugs
P38	Stefan Koestler - Determining the dynamic arrangements of repair factors during homology dependent DNA repair by super-resolution microscopy
P40	Adedoyin Adeyemi - Exploring the link between Transcription and Translation in Fission Yeast
P42	Shaleen Glasgow - Comparative transcriptomics of Daphnia and Bio-medical models for the evolutionary conservation of a gene network for fatty liver disease
P44	Christy Susan Varghese - Understanding oncogene-induced replication stress in tumorigenesis using HPV disease model
P46	Leona Irwin - Illustrating the role of lysine-specific demethylase 1 in early mammalian development using an intrinsic protein degradation system
P48	Luis Padilla-Cortes - Structural characterization of SPEN’s IDR and its role the formation of gene silencing supramolecular complexes
P50	Eve Dixon - The role of BAHD1 in heterochromatin formation and maintenance during early embryonic development