Programme

Conference Schedule and Confirmed Speakers

Wednesday 6th September

17.00-19.00
Registration opens                                                                                                                                                                               
19.00 - 21.00
Light buffet/dinner


Thursday 7th September 

09.00 - 09.20            
Arrival refreshments
09.20 - 09.30
Chris Bunce and Farhat Khanim
Welcome and Introduction to meeting
09.30 - 10.15 
Yuhan Zhao
(University College London, UK) 
A Unique Mode of Coenzyme A Binding to the Nucleotide Binding Pocket of Human Metastasis Suppressor NME1
10.15 - 10.45
Santosh Lomada
(University Clinic, Mannheim, Germany)
High resolution crystal structure of NDPK C and hetero-oligomerisation with other isoforms
10.45 - 11.15
Refreshment break
11.15 - 12.30
Malgorzata Tokarska-Schlattner
(Université Grenoble Alpes, France)
Knock-out of mitochondrial NME4
12.30 - 13.00
Maja Herak-Bosnar
(Ruđer Bošković Institute, Zagreb, Croatia)
Novel mitochondrial functions of NME6
13.00 - 14.30
Lunch 
14.30 - 15.15
Tom MacVicar
(Beatson Institute, Glasgow, UK)
NME6 and mitochondrial nucleotide metabolism
15.15 - 15.45
Özlem Yilmaz                                       
(Medical University Of South Carolina, USA)
Prolonged Heat-Shock-Protein-27 Phosphorylation by P. gingivalis’ Nucleoside-Diphosphate-Kinase Inhibits Autophagolysosomal Trafficking 
15.30 - 16.00
Refreshment break
16.00 - 16.45
Chris Bunce                                     
(University of Birmingham, Birmingham, UK)
Pathogen and human NDPK-proteins promote AML cell survival via monocyte NLRP3-inflammasome activation
16.45 - 17.30
Erle Robertson                                         
(University Of Pennsylvania, Philadelpia, USA)
Oncogenic viruses and regulation of Nm23-H1
18.30 - 21.00
Dinner

Friday 8th September 

09.00 - 09.30                    
Refreshments
09.30 - 10.15 
Shantanu Chowdhury
(Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India)
NME2 a Non-conventional Transcription Modulator: Connects Non-Duplex DNA Structure and Epigenetic Regulation
10.15 - 10.45
Farhat Khanim                               
(University of Birmingham, Birmingham, UK)
NM23-H1/NME1 in Diffuse Large B cell lymphoma
10.45 - 11.15
Refreshment break
11.15 - 12.30
Mathieu Boissan                             
(Sorbonne Université, INSERM, Paris, France)
Mechanisms of action of NME metastasis suppressors – a family affair
12.30 - 13.00
Jia Ning                                                         
(Salk Institute for Biological Studies, La Jolla, USA)
NME1/2 Histidine Kinase and PHPT1 Histidine Phosphatase Regulate Different Cellular Functions in Cancer
13.00 - 14.30
Lunch 
Poster Session 1
14.30 - 15.15
Domenico Luso                              
(University of Teramo, Teramo, Italy)
NME1/2-mediated mechanism governing De Novo Fatty Acid Synthesis unveils surprising crosstalk between intermediary metabolism and epigenetic regulation
15.15 - 15.45
Tom Wieland                                     
(Heidelberg University, Experimental Pharmacology Mannheim, Germany)
Inhibition of Nucleoside Diphosphate Kinase B/C Complexes as a Novel Therapeutic Option in the Treatment of Heart Failure
15.30 - 16.00
Refreshment break
16.00 - 16.45
Massimo Zollo                                                 
(CEINGE Biotecnologie Avanzate, Naples, Italy)
Mechanism of inhibition of Metastatic Gr3/4 Medulloblastoma by targeting NME/NM23 and Prune-1
16.45-15.30
Ivan Gout                                         
(University College London, UK)
Investigating the mode of NME1 regulation by a key metabolic integrator coenzyme A
15.30 - 16.00
IJMS
Discussion re Special Issue of IJMS
19.00 - 22.00
Conference Dinner

Saturday 9th September 2023

09.00- 09.30          
Refreshments
09.30 - 10.15            
Krisztina Takács-Vellai                     
(Eötvös Loránd University, Budapest, Hungary)
EV-mediated NME1 and NME2 modify lipid metabolism in fibroblasts
10.15 - 10.45
Michael Cross                    
(Universitätsklinikum Leipzig AöR, Leuipzi, Germany)
NME2 supports low energy signalling in hematopoietic progenitor cells
10.45 - 11.15
Refreshment break

11.15 - 12.30
Fatemeh Asadzadeh                          
(CEINGE, Biotecnologie Avanzate, Naples, Italy)
A murine model of TNBC tumorigenesis disregulate metabolic pathways enhancing NM23H1-H118F phosphorylation and immune system
12.30 - 13.30
Uwe Schlattner                                    
(Université Grenoble Alpes, France)
Meeting Summary and awards ceremony
13.30 - 14.30
Lunch

There will be tours of the University of Birmingham campus that will include the art gallery – The Barber Institute, the Botanical Gardens and the Lapworth Museum on the afternoon of Saturday 9th September.



Contact Us

University of Birmingham's Event Management Team

E: academic.conferences@contacts.bham.ac.uk