steve Matthews

Steve Matthews is Professor of Chemical and Structural Biology at Imperial College London and the Director of the Cross-Faculty NMR Centre (CF-NMR). Prof Matthews trained as a chemist and received his BSc (1987) and PhD (1990) degrees from the University of London.  His interest in spectroscopy developed from applying novel nuclear magnetic resonance (NMR) methods to the study of materials and rheological properties of lubricants.  After a period of postdoctoral training in the Chemistry Department at Imperial College (1990-1992), he moved to Oxford where he held an MRC Career Development Fellowship in the group of Professor Iain Campbell FRS.  He joined Imperial as a Lecturer in Biochemistry in 1996, became Reader in Structural Biology in 2002 and was promoted to his current position in 2004.

Research Interests

Diseases caused by pathogens such as bacteria, viruses, fungi and protozoa represent major challenges to humanity and its activities, impacting on quality of life, economic performance and food/water security. My research interests focus on unravelling the structural mechanisms by which pathogenic species attack their eukaryotic hosts. My group employs multi-disciplinary and complementary methods that aim to marry biological insight with quantitative data. In addition to employing a diverse array of molecular and structural tools, we are developing new nuclear magnetic resonance (NMR) methods to assist in mapping molecular flexibility and interactions in large assemblies. Prof Matthews’ biography comprises >200 peer-reviewed publications.